Dermal Fillers: Comparing Restylane, Juvederm, and Radiesse

Woman after dermal fillers Dermal Fillers: Comparing Restylane, Juvederm, and Radiesse

Dermal fillers are an excellent, non-surgical way to smooth lines, wrinkles and more. What differentiates a broad range of dermal fillers offered by dermatologists is where and what they treat. Let’s look at the options.

What to Know About Dermal Fillers

Dermal Fillers Explained

Most dermal fillers are solutions containing hyaluronic acid, a natural element within skin. Another kind of dermal filler uses calcium hydroxyapatite (CaHA), which acts as a filler and encourages collagen production. Dermal fillers are administered by injections, so there is no need for anesthesia or long recovery. As a result of their ease and simplicity, dermal fillers can be administered by your dermatologist in their office.

Dermal fillers do not produce permanent results and require maintenance treatments to reach and maintain desired outcomes. Results generally can last up to one year. Dermal fillers have a few applications, but the principle behind them is the same no matter where they’re used. The hyaluronic acid or CaHA helps restore skin’s natural fullness and smoothness.

Unlike some other cosmetic services like BOTOX, dermal fillers have applications beyond facial wrinkles. Where and what a dermal filler is approved to treat is the biggest thing that sets it apart from the others. Their ingredients may differ, but they produce results in a similar way with low-risk, temporary side effects. Common side effects of dermal fillers include bruising, redness, swelling, and infection. These are less common when administered by a dermatologist who holds your health as the highest priority.

A Brief Lesson in Hyaluronic Acid and Calcium Hydroxyapatite

Hyaluronic acid is a naturally occurring substance in our skin that provides elasticity and fullness. It aids in water retention, which helps make our skin look full and healthy. Hyaluronic acid is also produced in the joints and eyes. As we age, our bodies produce less and less hyaluronic acid. Certain dermal fillers were created to help supplement our natural hyaluronic acid production and promote healthier looking skin.

Calcium hydroxyapatite (CaHA) is not a naturally occurring substance in skin, but it works to supplement our body’s natural production of collagen, another important element in our skin’s structure. Collagen is produced in the middle layer of our skin (the dermis) and it is the main protein contained within skin. Because collagen production also slows with age, CaHA gives the collagen a much-needed push to help refill sagging or wrinkled skin.

Restylane® (formerly Perlane)

Restylane, Restylane Lyft, and Restylane Silk are dermal fillers that use hyaluronic acid to smooth and reduce wrinkles in the hands, lips, and face. Restylane was originally designed to treat facial wrinkles under the name Perlane. It has now been rebranded as Restylane – a suite of cosmetic dermal fillers using hyaluronic acid.

Restylane Lyft is used to treat the backs of hands that have become sunken or veiny. Restylane Silk is administered to provide silkier, smoother, and fuller looking lips. Silk can also treat wrinkles around the mouth.


Juvederm is similar to other hyaluronic acid injectables, but it also has particular perk Juvederm has a number of specialised applications and concentrations for treating cheek wrinkles, lips, and lip lines and wrinkles around the nose and mouth, to list a few.


Radiesse is a bit different from the other dermal fillers in that it doesn’t use hyaluronic acid. Instead, Radiesse uses gel microspheres made of calcium hydroxyapatite which help fill and stimulate collagen production. Radiesse is generally applied to the lower face (smile lines, chin wrinkles, pre-jowl folds) and the hands. Radiesse has been successful in reducing lines and wrinkles, as well as sagging skin in the lower face and hands.

Dermal Fillers: A Post-Script

Depending on where your body shows signs of aging, your dermatologist may recommend different products and services. Dermal fillers are not all the same, even if they share ingredients. People’s bodies react differently to different treatments. Based on your previous interactions, health conditions, and concerns, your dermatologist will explore your options in a consultation before proceeding with any particular treatment

Don’t let your skin show your age. Reach out to a trusted New England dermatologist for a consultation today!

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